34 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... - APLS • Acute ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Tamponade Pulmonary ... Vasculature: - PE - Pulmonary ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... #pulmonary
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute ... Myelodysplastic syndrome ... Differential #Diagnosis #Causes ... #hematology #secondary
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... transformation to acute ... Myelodysplastic #Syndrome ... Management #treatment #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... and Acute Fatty ... Pregnancy (AFLP) Three syndromes ... child * Severe cases ... AFLP #obstetrics #hematology
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Mastocytosis - Acute ... Hypereosinophilic Syndrome ... Differential #Diagnosis #Causes ... #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Malignant tumors, Acute ... PD deficiency, Pulmonary ... Hemolytic uremic syndrome ... #differential #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... Imaging: CXR- pulmonary ... Differentiation #Syndrome ... diagnosis #management #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
kidney disease, Acute ... Myelodysplastic syndrome ... differential #diagnosis #causes ... #hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... heart failure, neurologic ... renal bruit or signs ... Causes: • Vascular ... Neurologic disorders