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diagnosis hematology management differential algorithm cardiology chronic hepatology hepatopulmonary leukemia mds monoclonal myelodysplastic sob abscess aplastic apml cancer capillary cardiomyopathy
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Causes of Dyspnea ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... : - Anemia • ... #pulmonary
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
Causes of Chronic ... Dyspnea - Differential ... Artery Disease • Stable ... Acute Coronary Syndrome ... - Other • Anemia
Causes of Dyspnea - Differential Diagnosis Algorithm Cardiac: • Dysrhythmia • Ischemia • Cardiomyopathy • Valvular disease
Causes of Dyspnea ... Cardiomyopathy • Valvular ... Superior vena cava syndrome ... • Anxiety • Anemia ... amzn.to/2LmUODZ #Dyspnea
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... #hematology #oncology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... Constitutional Syndromes ... Treatment: ... #oncology #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... Causes of false- ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... Imaging: CXR- pulmonary ... diagnosis #management #hematology ... #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Pulm: Hypoxia, dyspnea ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
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