37 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Etiology: • Vascular ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Antiphospholipid-antibody syndrome ... • Vasculitis ... #joint #pain #skin ... differential #diagnosis #rheumatology
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Vascular Joint Pain ... Hyperemia Spasm • Vasculitis ... Air Embolism • Vasculitis ... Marfan's Syndrome ... #Orthopedics #Causes
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
CRYOGLOBULINEMIA (type l) : Vascular ... necrosis • Pain ... Hyperviscosity syndrome ... and Ill) • Vascular ... #Diagnosis #Rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Avascular necrosis ... BrighamChiefs #Bone #Joint ... differential #diagnosis #causes ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... Non-bloody: OA, avascular ... Like in this case ... #Joint #Pain #MSK ... #rheumatology #
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... Pulmonary HTN - Vasculitis ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... Deconditioning - Pain
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... splenomegaly, abnormal neurology ... , back pain Haematology ... cell disease Rheumatology ... discrepancy, multiple joint
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
Uveitis or retinal vasculitis ... , medium-large joints ... ) • Vascular lesions ... and peripheral vascular ... Diagnosis #criteria #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... arteritis, Cogan's Syndrome ... Polyarteritis Nodosa (PAN ... ANCA associated vasculitis ... Differential #Diagnosis #rheumatology