51 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Like in this case ... #Joint #Pain #MSK ... #rheumatology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... lesions • Discoid lupus ... #joint #pain #skin ... differential #diagnosis #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... Anti-retrovirals, Gemcitabine Lupus ... Diffuse muscle pain ... uncommon 5-15% of lupus ... diagnosis #comparison #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Avascular necrosis ... BrighamChiefs #Bone #Joint ... differential #diagnosis #causes ... #hematology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
involving small joints ... pain / swelling ... narrowing) • Ultrasound ... exam and imaging Treatment ... diagnosis #management #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... ) Inflammatory joint ... pain (especially ... and fingers, or pain ... erythematosus #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... phenomenon (20%) Joints ... Arthritis in small joints ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... Malignancy - Night pain ... neurology, back pain ... cell disease Rheumatology ... discrepancy, multiple joint
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Pain History ... : Is the pain from ... Disease: • Pain ... osteopetrosis, avascular ... #Pain #MSK #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... autoantibodies that will cause ... Puncture, EEG Treatment ... CNS #neurology #rheumatology ... diagnosis #management #treatment