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diagnosis hematology differential management algorithm bruising oncology physicalexam workup anemia aplastic approach arterial arthritis atopic atopy classification clinical coagulation cryofibrinogenemia
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Renal Disease Vascular ... TeIangiectasia Vascular ... • Steroids • Vasculitis ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Etiology: • Vascular ... Disruptions in vascular ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
Kaposi's sarcoma • Rheumatologic ... Autoimmune: ANCA-Assoc vasculitis ... Heart failure Vascular ... Nasopharyngeal bleeding ... Diagnosis #pulmonary #causes
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... Classify severity Treatment ... by a hemophilia treatment ... Diagnosis #Management #treatment ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Treatment: ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... Vascular Sludging ... classification #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Disruptions in vascular ... Infection - Vasculitis ... • Abdominal ultrasound ... #dermatology #physicalexam
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
• Disorders of vascular ... discern these causes ... Disruption in vascular ... integrity == • Vasculitis ... Differential #Diagnosis #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
considered in all cases ... coagulation and other causes ... 19 - PNH - Vasculitis ... pathophysiology #hematology ... differential #diagnosis #vascular
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Hyperviscosity, - Vascular ... Paradoxical spontaneous bleeding ... malignancies, vasculitis ... cryoglobulins • Negative causes ... #hematology
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