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diagnosis hematology differential algorithm antiphospholipid apls arterial bleeding bruising cryofibrinogenemia embolism hemostasis hypercoagulable management mds myelodysplasia myelodysplastic neutropenia nonpalpable oncology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... , Vasculitides, ... Diagnosis #Algorithm #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Disruptions in vascular ... deficiency Work ... • Abdominal ultrasound ... #dermatology #physicalexam
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... coagulation and other causes ... 19 - PNH - Vasculitis ... pathophysiology #hematology ... differential #diagnosis #vascular
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Out Secondary Causes ... factor (GCSF) treatments ... Workup: • Complete ... #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... neutropenia in collagen vascular ... #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Hyperviscosity, - Vascular ... malignancies, vasculitis ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
• Disorders of vascular ... von Willebrand syndrome ... discern these causes ... integrity == • Vasculitis ... Differential #Diagnosis #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... #Rheumatology #
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... Hypercoagulable Workup ... FOR TESTING: • Vascular ... maternal chromosomal causes ... Algorithm #diagnosis #hematology
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