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nephrology management treatment pharmacology potassium classification drugs high hypokalemia hypomagnesemia hypomg rhabdomyolysis workup acidosis algorithm cardiology cardiomyopathy diuresis diuretics elevation
Vasopressors and Inotropes - Pharmacology Summary Vasopressors Phenylephrine (alpha-1) • Increases BP, SVR • Risk of reflex bradycardia
Summary Vasopressors ... • Higher doses cause ... Dose dependent receptor ... cAMP/cGMP • Causes ... #medications
Drugs causing hyperkalemia • Impaired release of renin: NSAIDs, Beta blockers, Cyclosporine, tacrolimus, Diabetes, Elderly •
Drugs causing hyperkalemia ... • Angiotensin receptor ... #medications #causes ... #differential # ... diagnosis
Common Medications Known to Prolong QTc Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide Vasopressors/inotropes - Epinephrine, norepinephrine,
dronedarone, dofetilide Vasopressors ... /inotropes - Epinephrine ... #Causes #differential ... #diagnosis #pharmacology ... #table
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
compartment - b2-receptor ... hypomagnesemia #Medications ... #differential # ... diagnosis #nephrology ... #Causes #hypomg
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
Hypernatremia - Differential ... Diagnosis GI losses ... in kidneys) - Medications ... #Diagnosis #Table ... #Causes
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Renal Loses - Medications ... Hypomagnesemia #Differential ... #Diagnosis #Low ... #Magnesium #Table ... Classification #Causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... Beta adrenergic receptor ... Medications 2. ... diagnosis #causes
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome • Diagnosis ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... #Pharmacology #Medications ... #Table
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... Beta adrenergic receptor ... Medications 2. ... diagnosis #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... only if no clear cause ... Elimination (see Table ... concurrent need for vasopressor
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