10 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... Workup Algorithm ... • Euvolemic (Low ... , Cushing syndrome ... #Workup #Algorithm
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Algorithm Consumption ... Production - Flow ... HLH syndrome 5. ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Algorithm Consumption ... Production - Flow ... HLH syndrome 5 ... #Algorithm #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Algorithm - Systemic ... Skin Lesions == Macules ... BUN: • Chronic renal ... Myelodisplastic syndrome ... #generalized #dermatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Hypergammaglobulinemic macular ... beds-renal, retinal ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
involves face: macules ... CBC • Confirm: Flow ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... occurs due to a low ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... Anaphylaxis, Acute Renal ... #management #hematology ... #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... acid, high LDH, low ... high d-dimer, low ... #HemeOnc #Diagnosis
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Antiphospholipid Syndrome ... Hypercoagulable Workup ... FOR TESTING: • Vascular ... #Algorithm #diagnosis ... #hematology