29 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
dose dependent injury ... (ie, acetaminophen ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Severe Acute Liver Injury ... Drug-Induced liver injury ... - Viral Hepatitis ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... , yang, sulfa, acetaminophen ... quinine, etc) - Viral ... Thrombocytopenia #Differential ... Diagnosis #Framework #hematology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... Cirrhosis • Chronic Viral ... Drug-induced liver injury ... #Tests #LFTs #Differential ... #Diagnosis #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... bacterial and viral ... Thrombocytosis #Platelets #Differential ... #Diagnosis #Algorithm
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... #Differential # ... Causes #Acute #algorithm ... #hepatology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Neutrophils - Differential ... Diagnosis Algorithm ... • Abscess • Viral ... #Diagnosis #Algorithm ... #Causes #Hematology
Autoimmune Hemolytic Anemia (AIHA)

WARM AHA
- Primary - Idiopathics
- Secondary
Infectious
 • Viral- HIV, EBV, HCV, HEV
 •
Infectious • Viral ... e.g. diclofenac, acetaminophen ... • EBV • Viral ... AIHA #Diagnosis #Differential ... #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Diagnosis Algorithm ... Others #LFTs #Hepatology ... #LiverEnzymes #Differential ... #Diagnosis #Algorithm
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
by Etiology - Differential ... Diagnosis Algorithm ... • Bleomycin Hematologic ... Leishmaniasis - Viral ... #Differential #