13 results
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
ejection fraction, treatment ... cardiovascular causes ... - Visual Abstract ... Cardiology #EBM #VisualAbstract
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... - Infection - Viral ... Treatment of underlying ... per day until stable ... Diagnosis #Management #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... arterial volume (↓distal ... 20 suggests ↓ distal ... only if no clear cause ... Elimination (see Table
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
goals of acute treatment ... Patients with chronic ... Figure 3 is an algorithm ... , and Table 3 summarizes ... #Treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... for alternative causes ... Hepatocellular: Viral ... e.g. ascites), Chronic
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
ETOH Infection (Viral ... per day until stable ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment
Randomized Controlled Trial of Intravenous Acetaminophen Versus Intravenous Hydromorphone for the Treatment of Acute Pain in
Hydromorphone for the Treatment ... the cost of more nausea ... and vomiting Visual ... Abstract by David ... dhcisewski #EBM #VisualAbstract
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Differential Diagnosis Algorithm ... Reduced flow through distal ... Creatinine • Chronic ... #Causes
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
liver cirrhosis, chronic ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... Tolvaptan) • Treatment ... #Medications #Table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... life-threatening • Treatment ... : Usual therapeutic ... • Evolution: Chronic ... sle #comparison #table