1381 results
Isolated Neutropenia - Differential Diagnosis Algorithm
Chronic (>3 months):
 • Extrinsic: Vitamins
 • Intrinsic: Congenital, Inflammatory
Transient:
 •
• Extrinsic: Vitamins ... Diagnosis #Algorithm #hematology
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
Homocysteine Levels in Vitamin ... VitaminB12 #diagnosis #hematology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Warfarin (Coumadin) → Vitamin ... #pharmacology #hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
kidney disease - Vitamin ... Underproduction #Algorithm #hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
consumption • Vitamin ... Differential #Diagnosis #Hematology
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Anticoagulants (Vitamin ... prolonged #diagnosis #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Elevated in: • Vitamin ... Thromboplastin #laboratory #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Liver Disease • Vitamin ... Algorithm #Causes #Hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Acquired: • Vitamin ... comparison #diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Megaloblastic: Vitamin ... diagnosis #causes #hematology