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management pharmacology antifungal diagnosis treatment infectiousdiseases antibiogram antibiotics coccidioides coccidioidomycosis coverage fusarium infections medications overview polyenes review sensitivities spectrum table
Antifungal Azoles - Antibiotics Class Overview Mechanism: inhibit ergosterol synthesis (important component of fungal cell membranes)
Voriconazole(PO ... #Itraconazole #Voriconazole
Antifungal Agents Frequently Used in Leukemia Antibiogram: • Fluconazole • Itraconazole • Voriconazole • Posaconazole • Caspofungin
Itraconazole • Voriconazole
Antibiotics and CNS Diffusion 1. Drugs with good CNS diffusion: - Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole 2. Drugs
, Fluconazole, voriconazole
Algorithm for Evaluation and Treatment of Asymptomatic Candiduria Evidence for disseminated candidiasis, Unstable or neutropenic patient 1. fluconazole
→ 100 mg/d 4. voriconazole
Spectrum of activity for systemic antifungal agents Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
posaconazole; VOR, voriconazole
Antifungal Coverage Activity Antibiogram Spectrum of action of systemic antifungal agents. Solid blocks represent species in
posaconazole; VORI = voriconazole
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview Mechanism: binds ergosterol in membrane and
aspergillosis (voriconazole
Common Medications Known to Prolong QTc Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide Vasopressors/inotropes - Epinephrine, norepinephrine,
itraconazole, voriconazole
Allergic Bronchopulmonary Aspergillosis (ABPA) WHAT IS IT? Hypersensitivity response to Aspergillus fumigatus in the airways • Primarily affects
itraconazole or voriconazole
Arthritis of the Hand - Arthritis Patterns Osteoarthritis: • Osteoarthritis of the hand usually involves the DIP and
A toxicity • Voriconazole
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