43 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential ... Abnormal peripheral smear ... • Extrinsic RBC ... #Differential # ... Diagnosis #Algorithm #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... cells: Sickle cell disease ... #Analysis #hematology ... #microscopy #interpretation ... #clinical #anemia
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... Bodies #Pathology #Hematology ... #Smear #Clinical ... #Microscopy
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Normochromic RBCs on Smear ... Disease • Marrow ... Spherocytes on Smear ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... anemia (sometimes ... #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Normal Blood Smear ... Cells, Normal WBCs ... • Liver Disease ... Algorithm #Causes #Hematology
Leukoerythroblastosis and myelophthisic anemia can be associated with any marrow-replacing process. In this case, the likely
myelophthisic anemia ... Leukoerythroblastosis #Hematology ... #Pathology #Smear ... #Microscopy #Clinical
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... , Drugs, Liver Disease ... Defects: Sickle cell anemia ... Peripheral Blood Smear ... #Diagnosis #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... DIC is a clinical ... arrow) Peripheral smear ... #Hematology #Pathology ... #Smear #Microscopy
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Artifact (redo CBC ... disorders • Celiac disease ... Iron deficiency anemia ... Algorithm #Causes #Hematology