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diagnosis hematology differential treatment causes dermatology gastroenterology neurology signs leukemia rheumatology systemic aplastic barre chestpain chronic cll disease functional generalized
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Definition • Pathophysiology ... Expectation • Rx Algorithm ... #Aplastic #Anemia ... #diagnosis #oncology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... malignancy: • Symptoms ... : B-symptoms, bruising ... hepatomegaly • Labs: anemia ... #hematology #WBC
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... Neutrophils - Low RBC ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... Differential #Diagnosis #Algorithm
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... blasts and high WBC ... • Lab values: WBC ... : • Pathophysiology ... TLS #diagnosis #management
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm Risk factors: Previous acute enteric infection, Female
(IBS) - Pathophysiology ... Diagnosis and Management ... Algorithm Risk ... factors affecting symptom ... #Pathophysiology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... treatment #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... APML #diagnosis #management ... #hematology #oncology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... experience some symptoms ... RBC are produced ... Approximately 1% of RBC ... destruction of RBC
Functional Dyspepsia - Pathophysiology, Diagnosis and Management Risk factors: Non-steroidal anti-inflammatory drugs, Psychological comorbidity, Helicobacter pylori infection,
Diagnosis and Management ... sex, Smoking Symptoms ... : Bothersome symptoms ... #Diagnosis #Management ... #algorithm #gastroenterology
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