136 results
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... Microcytic - Iron-deficiency ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... coagulopathy (DIC) #RBC
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... B12 or Folate deficiency ... deficiency, Unstable ... elliptocytosis, Severe iron deficiency
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased WBCs ... Normal/lncreased WBCs ... • Early Iron Deficiency ... #Normocytic #Anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Neutrophils - Low RBC ... • Dietary Deficiency ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... B12 and Folate Deficiency
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... • Improve the symptoms
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... • Aplastic Anemia ... • Anemia of Chronic
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
malignancy: • Symptoms ... : B-symptoms, bruising ... hepatomegaly • Labs: anemia ... platelets, persistent WBC ... Algorithm #hematology #WBC
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach to Anemia ... inflammation) • Iron deficiency ... Spherocytosis, G6PD, PK, HbC ... Megaloblastic: Folate deficiency ... , B12 deficiency
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
== Decreased RBC ... -12, or folate deficiency ... Hypertriglyceridemia • Uremia ... Glucose Content • RBC ... • Hemolytic anemia
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... E - Haemolytic anaemia ... Wernicke-Korsakoff syndrome ... #Vitamins #Deficiency ... diagnosis #signs #symptoms