26 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... - CD7, CD3 Chronic ... • Lymphoid (CLL ... bcr-able (+) ↑ WBC ... #hematology #Markers
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential ... Artifact (redo CBC ... • Rheumatic disorders ... effect following treatment ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... (Pancytopenia, WBC ... Age > 50 • Chronic ... #Causes #Hematology ... #Oncology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Diagnosis Algorithm ... RBCs on Smear • Chronic ... Membrane Disorder ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential ... inflammatory disorders ... myeloid leukemia (CML ... #Diagnosis #Causes ... #hematology #secondary
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... not required in all ... Diagnosis #Causes ... #Workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... ) (e.g. lupus, CLL ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... lymphoproliferative disorders ... microglobulin Treatment ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... leukemia in adults • Disorder ... immunophenotype Clinical ... #Leukemia #oncology ... #hematology #hemeonc
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Diagnosis Framework ... Myeloproliferative Disorders ... : • Chronic myeloid ... #Diagnosis #causes ... #hematology #basophils