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rheumatology sle classification patterns antibody antineutrophil aortitis arthritis autoantibodies autoimmune bee cryoglobulinemia cryoglobulins dermatology diseases inflammatory laboratory management mimickers myopathy
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... lupus erythematosus ... lupus erythematosus ... #Antibodies #ANA ... #diagnosis #differential
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... • Sjögren syndrome ... #antibodies #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... lupus erythematosus ... , Sjögren Syndrome ... #Antibodies #ANA ... #diagnosis #differential
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
arthritis (RA) ... or systemic lupus ... SLE) Signs / Symptoms ... #Syndrome #Pathophysiology ... #Diagnosis #Signs
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
• Sjögren syndrome ... • Systemic lupus ... erythematosus ... spectrum disorder • ANCA-associated ... vasculitides •
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
, Cogan's Syndrome ... Nodosa (PAN), ANCA ... (RA), Systemic ... lupus erythematosus ... #Diagnosis #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis) - ANCA-negative ... lupus erythematosus ... testing: anti-ANCA ... , anti-GBM ab, ANA ... diagnosis #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... Diagnosis: Systemic ... lupus erythematosus ... Symptoms (Sx) in ... differential #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... Serositis Labs: • ANA ... • (-) ANA + (+ ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... ) Blood (75%): Anemia ... #erythematosus # ... signs #symptoms ... #diagnosis #rheumatology
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