WBC diagnosis hematology symptoms causes rheumatology syndrome systemic dermatology hemolytic secondary pathophysiology treatment

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Pathophysiology, Signs and Symptoms of Hemolytic Anemia

#Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms

Pathophysiology, ... Signs and Symptoms ... of Hemolytic Anemia ... #hematology #diagnosis ... #signs #symptoms

Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
- Decreased/NormaI

Causes of Anemia ... - Differential Diagnosis ... Hypersplenism • Secondary ... #Algorithm #Causes ... #Hematology

Warm Antibody Autoimmune Hemolytic Anemia
1) DIAGNOSE AIHA
• Anemia: macrocytic > normocytic, ↑ reticulocytes
•

↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... → Systematic screening ... #management #treatment ... #rheumatology

Hypereosinophilia and Hypereosinophilic Syndrome

• Secondary Hypereosinophilic Syndrome
• Clinically Relevant HES Variants
• When to

• Secondary ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophils #diagnosis

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... Extravascular Causes ... uremic syndrome ... • Intrinsic RBC ... #hematology #anemia

Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
-

Causes of Extravascular ... - Differential Diagnosis ... elliptocytosis - RBC ... #Algorithm #Causes ... #Hematology

Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
- Systemic Inflammatory
•

Causes of Diffuse ... - Differential Diagnosis ... Reactive: - Systemic ... (Pancytopenia, WBC ... #Hematology #Oncology

Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
• Acute infection
• Solid organ

Causes of Thrombocytosis ... iron deficiency, hemolysis ... Myelodysplastic syndrome ... #Causes #hematology ... #secondary

Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage

- Differential Diagnosis ... leakage of RBC's secondary ... DIC/TTP/HUS - Hemolytic ... #hematology #rheumatology ... #nonpalpable #dermatology

Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
• Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity

blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... #TLS #diagnosis ... #management #hematology

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