36 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... ) Step 3: Is a Systemic ... Disease Prolonging ... to identify the cause ... #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... Destruction • Abnormal ... #Causes #Hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Diagnosis Algorithm ... RBC Mass / Decreased ... Chronic Chest Symptoms ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Diagnosis Algorithm ... Myelodysplastic Syndromes ... WBCs - Normal ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
: INR/PT, aPTT(liver ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... #Diagnosis #Causes ... #Workup #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
sweats, pallor, bruising ... splenomegaly, abnormal ... neurology, back ... pain Haematology ... Rheumatology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... associated with systemic ... amyloidosis #Abnormal ... #Causes #diagnosis ... hematology #coagulation
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Drug-associated, PCH, Evans Syndrome ... Blood Smear ↑ abnormal ... #Diagnosis #hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... antiphospholipid syndrome ... #differential # ... hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Diagnosis Algorithm ... Production - Normal ... Anemia of Chronic Disease ... #Causes #Hematology