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differential aki anemia aplastic apml cancer classification coagulation dic differentiation disseminated diuresis diuretics encephalopathy excretion hepatitis intravascular leukostasis liver lysis
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... Cancer Related • Hypercalcemia ... gammopathy of renal ... malignancies Treatment ... #Kidney #Injury
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Causes of Acute ... hepatitis: < 1 • Cirrhosis ... intestines, white blood ... #algorithm #hepatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Summary Causes ... UA positive for blood ... nephrotoxicity to kidney ... #Management #causes ... #treatment #nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
count cause hyperviscosity ... - ACS, AKI, acute ... hydration - Hyperkalemia ... #TLS #diagnosis ... #management #hematology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Diagnosis of ... irrigation • Management ... stones caused by ... Prevention of blood ... Tolvaptan) • Treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Pathophysiology ... Renal Failure ... #management #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... and petechiae Causes ... result from low blood ... #hematology #diagnosis ... #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... ABO incompatible blood ... Bleeding (64%) • Renal ... #causes #treatment ... #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Immunosuppressive agents, Renal ... transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... #diagnosis #management ... #neurology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
, DIC, hypoTN, renal ... Lung Injury (TRALI ... Hypocalcemia, Hyperkalemia ... #Transfusions #diagnosis ... #management #hematology
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