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hematology neurology differential syndrome algorithm oncology rheumatology anemia gastroenterology pulmonary renal summary autoimmune barre chronic cirrhosis crisis deficiency encephalopathy gravis
Hypereosinophilia (HE) Summary • Definition • When to Suspect? • A Partial Classification of Hypereosinophilia •
• A Partial Classification ... Hypereosinophilia • Diagnostic ... Presentations • Treatment ... Hypereosinophilia #HE #hematology ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... Syndrome #TLS #diagnosis ... #management #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Non-lmmune #Anemia #Classification ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... Artifact (redo CBC ... effect following treatment ... #Hematology
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
RBC casts in urine ... but in severe cases ... Nephrotic #Syndromes #Classification ... #Proteinuria #Nephrology ... #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... if high risk if WBC ... QD until normal WBC ... #management #hematology
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Nephritis #SLE #Classification ... #Classes #differential ... #diagnosis #management ... #nephrology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... intralobular bile ducts causes ... Diagnosis: • ... Differential Diagnosis ... #workup #hepatology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia 1) DIAGNOSE ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... Hemolytic #Anemia #diagnosis ... #management #treatment
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