6405 results
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... Features of hematologic ... platelets, persistent WBC ... #Algorithm #hematology ... #WBC #Leukemoid
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... (Pancytopenia, WBC ... Lymphocytic Leukemia (CBC ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... Even with normal WBC ... counts may delay diagnosis ... #differential #diagnosis ... #CBC #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... bcr-able (+) ↑ WBC ... Blood #Disorders #hematology ... #Differential #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if high risk if WBC ... opacities • Diagnosis ... • Differential Diagnosis ... QD until normal WBC ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... • Lab values: WBC ... Syndrome #TLS #diagnosis ... #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... from ischemia WBC ... ThromboticThrombocytopenicPurpura #Diagnosis ... #Workup #Hematology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... Framework HEMATOLOGIC ... Leukostasis: • WBC ... #differential #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... Anemia #oncology #hematology ... #diagnosis #management
Interpretation of Components of the CBC (Complete Blood Count)

#CBC #Interpretation #CompleteBloodCount #Hematology #Differential #Diagnosis #Laboratory
Components of the CBC ... Blood Count) #CBC ... CompleteBloodCount #Hematology ... #Differential #Diagnosis