24 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Systemic Lupus Erythematosus ... (Pancytopenia, WBC ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Atypical HUS, autoimmune ... antiphospholipid syndrome ... Systemic Lupus Erythematosus ... #differential #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
disease • Non-autoimmune ... rheumatologic diseases ... Malignancy (e.g. hematologic ... deficiencies • Autoimmune ... #Diagnosis #Rheumatology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... : 2-8 weeks • Rash ... : Painful erythematous ... #SJS #TEN #comparison ... #table #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... • Intrinsic RBC ... differential #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... diagnosis #management #hematology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
malignancies, autoimmune ... presenting with erythematous ... infection and autoimmune ... PrathitKulkarni #Erythemas #comparison ... differential #diagnosis #dermatology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Causes of false- ... plasmacytoma, POEMs syndrome ... macroglobulinemia, and autoimmune ... MGUS #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... if high risk if WBC ... diagnosis #management #hematology ... #oncology