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differential algorithm management anemia causes workup oncology treatment blood comparison intravascular syndrome atlas autoimmune hemolysis laboratory liver microscopy morphology pathophysiology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential Diagnosis ... • Extrinsic RBC ... • Intrinsic RBC ... #Differential #Diagnosis ... #Algorithm #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Bleed • Hemolysis ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... Algorithm #Causes #Hematology
Pathophysiology of Hemolytic Anemia - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects) -
Pathophysiology of Hemolytic ... - Defects in RBC ... - Defects in RBC ... Pathophysiology #Hemolytic ... #Anemia #hematology
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
Hct of 70-80% - RBC ... plasma, a few RBC ... proteins, all coagulation ... Contents #Volume #Hematology ... #Management #Table
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... Asplenism, Severe hemolytic ... Sickle cell, MDS #RBC ... Inclusions #Bodies #diagnosis ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... intravascular coagulation ... • Intrinsic RBC ... #differential #diagnosis ... #hematology #anemia
ABO Blood Types and Transfusion Compatibility Table A Blood Type: • RBC Antigens: A • Antibodies: Anti-B
Blood Type: • RBC ... Blood Type: • RBC ... Blood Type: • RBC ... Blood Type: • RBC ... #hematology
Interpretation of Components of the CBC (Complete Blood Count) #CBC #Interpretation #CompleteBloodCount #Hematology #Differential #Diagnosis #Laboratory
Components of the CBC ... Blood Count) #CBC ... CompleteBloodCount #Hematology ... #Differential #Diagnosis
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... 2) External (RBC ... 3) Internal (RBC ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... - Differential Diagnosis ... elliptocytosis - RBC ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
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