19 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... of anemia and hemolysis ... Anemias (AIHAs) ... Anemias (AHAs) ... #Diagnosis #Algorithm
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... WBCs - Decreased ... Anemias (MAHA) ... #Normocytic #Anemia ... #Hematology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
thrombocytopenia, Autoimmune Hemolytic ... anemia, Penicillin-induced ... #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
) Morphology Atlas ... spherocytosis, Hemolytic ... #Morphology #Atlas ... #key #diagnosis ... #differential #hematology
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
hypersensitivity reactions ... Hours to Days (Hemolytic ... Anemia) Type ... #Types #Classification ... #Allergy #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... Other: Transfusion reaction ... • Intrinsic RBC ... #hematology #anemia
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Sideroblastic anemia ... anemia Stomatocyte ... #differential #diagnosis ... #atlas #nomenclature
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
to Anemia - Differential ... Sideroblastic anemia ... ACD, Aplastic anemia ... MatthewHoMD #Anemia ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Deficiency • Aplastic Anemia ... • Anemia of Chronic ... Non-lmmune #Anemia ... #Classification
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
for Hemolytic Anemia ... • Transfusion reactions ... #Anemia #Differential ... #classification ... #hematology