10 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential Diagnosis ... Drug-induced AIHA - Abnormal ... anemia • Acute ... • MAHA (TTP, DIC ... #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Malignant tumors, Acute ... PD deficiency, Pulmonary ... uremic syndrome ... coagulopathy (DIC ... #Atlas #key #diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
MAHA: TTP, HUS, DIC ... Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Blood Smear ↑ abnormal ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... vein: Budd-chiari syndrome ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
(hemolysis) • ... • Gilbert's syndrome ... • Hemolysis ... #diagnosis #differential ... #Hepatology #transaminitis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
necrosis HELLP Syndrome ... and hemorrhage Acute ... DIC • Aminotransferases ... Disease #Pregnancy #hepatology ... #differential #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... if high risk if WBC ... Imaging: CXR- pulmonary ... WBC • Continue ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... • Severe Liver ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... pain, dark urine, DIC ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... coronary syndrome ... #algorithm #management ... #cardiology #treatment ... heartfailure #chf #criticalcare