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rheumatology hepatology sclerosis workup antibodies oncology algorithm als amyotrophic ana antinuclear associations autoantibodies behcet cholangitis chronic cll dermatology differential diseases
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’ ... biliary cirrhosis ... (PBC), or with ... systemic diseases ... #Diagnosis #Signs
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... consistent with PBC ... #PBC #Primary ... #Biliary #Cirrhosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... Pathophysiology ... Signs and Symptoms ... #Biliary #Cirrhosis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
, Anti-gp210 - Primary ... biliary cirrhosis ... (PBC) Anticentromere ... Anti-SSB (La) - Sjogren's ... #diagnosis #table
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... and Symptoms: ... pericarditis • Hepatic: PBC ... (primary biliary ... #diagnosis #signs
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... • Lab values: WBC ... >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... erythematosus (SLE), Sjogren's ... Autoimmune Hepatitis, Primary ... Biliary Cirrhosis ... #diagnosis #differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... biliary cirrhosis ... #Syndrome #Rheumatology ... #Diagnosis #Management
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... #PBC #Primary ... #Biliary #Cirrhosis ... #Management #Treatment
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Episcleritis Signs ... - CBC may also ... Treatment: - Systemic ... #diagnosis #dermatology
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