7 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential ... Diagnosis Algorithm ... Artifact (redo CBC ... effect following treatment ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... T-cell - CD7, CD3 Chronic ... bcr-able (+) ↑ WBC ... #Diagnosis #Algorithm
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... Chronic CPP Crystal ... Synovial Fluid: • WBCs ... • Metabolic syndrome ... Gout #Comparison #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... if high risk if WBC ... initiation • Differential
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
) Pathophysiology ... Chronic CPP Crystal ... Synovial Fluid: • WBCs ... Acute Pseudogout: Treatment ... Crowned Dens Syndrome
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
(ET) ET is a chronic ... , RBCs & WBCs are ... and aside from thrombocytosis ... associated with thrombocytosis ... • Treatment algorithms