242 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... glomerular hematuria (RBC ... casts or dysmorphic ... Comparison #Algorithm #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... urine sediment - WBC ... /RBC casts ... #Proteinuria #Nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
of UTI, urine WBCs ... (proteinuria, RBC ... casts, dysmorphic ... → Refer to Nephrology ... if cause not identified
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... hematuria: - RBC ... • Nutcracker syndrome ... #urology #nephrology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased WBCs ... Normal/lncreased WBCs ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... (Pancytopenia, WBC ... Lymphocytic Leukemia (CBC ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
dysmorphic RBC’s, RBC ... /WBC casts, proteinuria ... Diagnosis #EM #IM #Urology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... decreased PLT count: CBC ... (CVID, WAS), (neurologic ... disease), HBsAg/anti-HBc ... #Workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... Diagnosis #Algorithm #Causes ... #Hematology