9 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... the patient have glomerular ... hematuria (RBC ... casts or dysmorphic ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... Nephritic syndrome—due ... RBC casts in urine ... diabetes)) #Glomerular ... #Proteinuria #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... • Drugs Glomerular ... urine sediment - WBC ... /RBC casts ... #Proteinuria #Nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
of Glomerular Bleeding ... disease - Alport syndrome ... pain hematuria syndrome ... • Nutcracker syndrome ... #urology #nephrology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... body-like: - Neurologic ... ARUPLabs #ANA #Antinuclear ... #Antibody #Testing ... differential #diagnosis #rheumatology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Sediment (dysmorphic RBC ... , RBC casts, +/- ... formation along glomerular ... anti-phospholipid syndrome ... Glomerulonephritis #MPGN #nephrology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... - NORMAL CSF WBC ... equina • GQ1b IgG Antibody ... management #treatment #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Stiff Person Syndrome ... Prevalence: 1-2 cases ... Pathophysiology ... levels of GAD, an antibody ... Management #treatment #neurology