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oncology causes chronic classification cll eosinophils hepatopulmonary lymphocytic anemia aplastic apml bandemia cbc cirrhosis coagulation dic differentiation disseminated eosinophil hemeonc
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Syndrome • Clinically ... disorders • Diagnosis ... and Treatment Algorithm ... #Hematology #eosinophilia ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Syndrome (HES) ... #Syndrome #HES ... #eosinophilia #diagnosis ... #hematology #differential ... #management #eosinophils
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... glucocorticoid treatment ... #Disorders #Algorithm ... #Differential # ... diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Chronic Myelogenous Leukemia ... • Rheumatic disorders ... #Diagnosis #Algorithm ... #Causes #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential ... Diagnosis Algorithm ... Treated Like Acute Leukemias ... Classification #pathophysiology ... #Hematology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Agent Orange or Hep ... C Clinical Presentation ... lymphoproliferative disorders ... microglobulin Treatment ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
in adults • Disorder ... immunophenotype Clinical ... #oncology #hematology ... #hemeonc #diagnosis ... #management
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Cell population has ... Tissue damage • Leukemia ... #WBC #CBC #hematology ... #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... - Hepatitis, eosinophilic ... virus (EBV) • Leukemia ... Anemia #oncology #hematology ... #diagnosis #management
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