11 results
diagnosis hematology oncology anemia causes eosinophils extravascular hemolysis hemolytic hypereosinophilia agglutinin aplastic apml bandemia cbc chronic classification coagulation cold dic
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
• Clinically ... Diagnosis and Treatment ... #HES #Hematology ... #eosinophilia # ... #management #algorithm
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... Diagnosis Algorithm ... • Sickle cell ... elliptocytosis - RBC ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(HUS) • Other ... ) (e.g. lupus, CLL ... • Intrinsic RBC ... #Causes #differential ... #diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
than 1500 and clinical ... #HES #eosinophilia ... #diagnosis #hematology ... #differential # ... management #eosinophils
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Agent Orange or Hep ... C Clinical Presentation ... Lymphocytosis on CBC ... microglobulin Treatment ... workup #oncology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Pathophysiology ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... population has ... #Bandemia #differential ... #CBC #hematology ... #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... protein C and S Pathophysiology ... organ damage Clinical ... hydration • RBC ... #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... - Hepatitis, eosinophilic ... • ↓ WBC • ↓ ... Anemia #oncology #hematology ... #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... the RBCs causing intravascular ... hemolytic #anemia #hematology
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