25 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... Intravenous fluids • Renal ... #TumorLysis #Syndrome ... #TLS #diagnosis ... #management #oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Hyperviscosity Syndrome ... Leukostasis: • WBC ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome ... #cancer
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
gammopathy of renal ... sinusoidal obstructive syndrome ... Capillary leak syndrome ... • Tumor lysis syndrome ... #Nephrology
Hypophosphatemia - Differential Diagnosis Algorithm

Transcellular Shift
 • Recovery From DKA
 • Refeeding Syndrome
 • Acute Respiratory
- Differential Diagnosis ... • Refeeding Syndrome ... Alkalosis • Hypokalemia ... Increased Excretion - Renal ... Osteomalacia • Fanconi Syndrome
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Algorithm Hypovolemia ... Cerebral salt wasting syndrome ... Stress, Drugs, Syndrome ... • Nephrotic syndrome ... #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... : • Hypovolemia ... Abdominal Compartment Syndrome ... #nephrology #causes ... #algorithm
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... diuresis, Bartter's syndrome ... use), Gitelman's syndrome ... excess and related syndromes ... #nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... - ACS, AKI, acute ... rasburicase Tumor Lysis Syndrome ... #Tumor #Lysis #Syndrome
Mesenteric Ischemia - Differential Diagnostic Schema
Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA)
Acute
 - Venous
GPA, IgA, MPA) Acute ... Antiphospholipid syndrome ... Hypoperfusion: Lumen (Bowel ... ), Meds/Treatments ... #algorithm
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Renal Failure ... Differentiation #Syndrome ... #management #hematology ... #oncology