13 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Arrhythmias / CHB ... Pericardial tamponade, Pulmonary ... vasoactive drug pharmacology ... Vasoactive #Drugs #pharmacology ... diagnosis #management #comparison
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... if high risk if WBC ... Imaging: CXR- pulmonary ... sepsis), PE, DAH, CHF ... QD until normal WBC
Coccidiomycosis - Diagnosis
Diagnosis:
 • Mildly elevated peripheral WBC, Eosinophilia (25%), Elevated ESR, Procalcitonin normal (95%)
 •
elevated peripheral WBC ... trend response to treatment ... Urine & Blood & CSF ... Glucan in blood/CSF ... Diagnosis #workup #infectiousdiseases
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... : Age>60, CKD, CHF ... , and CXR with pulmonary ... : No • Treatment ... hematology #diagnosis #comparison
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis.
Fluconazole - Low
Overview of antifungal ... effects in the treatment ... valleyfever #management #treatment ... #antifungals #comparison ... #table #pharmacology
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
echocardiography - CBC ... in cardiogenic pulmonary ... hypoperfusion, no pulmonary ... Revascularization, treatment ... #Checklist #CHF
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... & Dry) is the treatment ... & Dry” is the treatment ... #heartfailure #chf ... icu #clinical #pharmacology
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
of prior silent pulmonary ... CSF wbc is generally ... Standard treatment ... initiation of antifungal ... initiation of antifungal
Antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis
Fluconazole
 - Benefits: Low cost/tolerable
Antifungal agents ... effects in the treatment ... chest/back pain #Antifungal ... Coccidioidomycosis #pharmacology ... #management #treatment
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
documenting successful treatment ... FDA-approved for UTI treatment ... outcomes when used in treatment ... Antimicrobials #InfectiousDiseases ... #Pharmacology