10 results
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... arrow) Peripheral smear ... conditions such as disseminated ... #Pathology #Smear
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
AIHA • Anemia ... ↑ LDH • Anti-RBC ... type ± C3d • Blood ... smear: Differential ... #management #treatment
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
A complete blood ... count (CBC) should ... as a peripheral smear ... microangiopathic hemolytic ... LaboratoryFindings #Disseminated
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... spherocytosis, Hemolytic ... thrombocytopenia (ITP), Disseminated ... coagulopathy (DIC ... key #diagnosis #differential
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... MAHA: TTP, HUS, DIC ... Defects: Sickle cell anemia ... - Peripheral Blood ... Smear ↑ abnormal
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
of Peripheral blood ... smear - Shows schistocytes ... from ischemia WBC ... count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... organ damage Clinical ... • Peripheral smear ... causes #treatment #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... younger pts) Differential ... sensitize red blood
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... platelets - WBC ... hematology #oncology #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Diagnosis: • CBC ... Leukocytosis, anemia ... • Sputum/Blood