19 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
in Hemolytic Anemia ... LDH Peripheral smear ... #Anemia #Laboratory ... #Testing #workup ... #diagnosis #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... #Smear #Analysis ... #hematology #microscopy ... interpretation #clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... and laboratory ... #anemia #Hematology ... #Microscopy
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
AIHA • Anemia ... ↑ LDH • Anti-RBC ... type ± C3d • Blood ... smear: Differential ... management #treatment #rheumatology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Microangiopathic Hemolytic ... differential #diagnosis #hematology ... #microscopy #atlas
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... - Peripheral Blood ... Smear ↑ abnormal ... Differential #Diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... of Peripheral blood ... smear - Shows schistocytes ... from ischemia WBC ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... for workup, including ... : Acute blood loss ... , Acute hemolysis ... , deficiency anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... plateletcount), peripheral blood ... smear, HIV/HCV ... changes), high MCV anemia ... #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
in peripheral blood ... High in acute blood ... loss, hemolysis ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic