41 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... #Smear #Analysis ... #hematology #microscopy ... interpretation #clinical
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... • Peripheral blood ... smear + DAT + further ... → Sickle Cell anemia ... Malaria, Clostridium
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Anemia 1) DIAGNOSE ... AIHA • Anemia ... ↑ LDH • Anti-RBC ... type ± C3d • Blood ... smear: Differential
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
multiples per RBC ... ~75% of human malaria ... #peripheral #clinical ... #microscopy #microbiology ... #malaria
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... arrow) Peripheral smear ... #Pathology #Smear ... #Microscopy
Plasmodium Falciparum Gametocytes on Blood Smear.

Banana-shaped gametocytes are only seen in Plasmodium falciparum but rare in
Smear. ... #Smear. ... #peripheral #clinical ... #microscopy #microbiology ... #malaria
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... diagnosis #hematology #microscopy
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Infections/toxins: Malaria ... Defects: Sickle cell anemia ... - Peripheral Blood ... Smear ↑ abnormal
Babesia spp. on Peripheral Blood Smear Microscopy
 - Multiple small parasites per RBC
 - "maltese cross"
on Peripheral Blood ... Smear Microscopy ... parasites per RBC ... richdavisphd #Babesia #clinical ... #smear
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... suspected, consider malaria ... ARUPConsult @ARUPLabs #Hemolytic ... #Anemia #Differential ... Diagnosis #Algorithm #workup