13 results
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Kidney Injury (AKI ... malignancies Treatment ... Interleukin-2) • Tumor lysis ... Kidney #Injury #AKI ... #Cancer #Oncology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... Clinical TLS: • AKI ... #TumorLysis #Syndrome ... diagnosis #management #oncology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... of the above Treatment ... Matthew Ho, MD ... #Syndrome #diagnosis ... #management #oncology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... #Tumor #Lysis ... #Syndrome #TLS ... #oncology #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Syndrome Leukostasis ... fever - ACS, AKI ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... tetany ↑UA = AKI ... above #Tumor #Lysis ... #Syndrome #TLS ... Pathophysiology #oncology
CML Treatment Free Remission (TFR) 

 • Goals of Therapy in CML
 • CML Rx Milestones
CML Treatment Free ... to discontinue TKI ... • TKI withdraw ... Zhuoer Xie, MD ... #CML #TFR #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... only curative treatment ... #MDS #Diagnosis ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
(MDS) (normal or ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... as internuclear ophthalmoplegia ... • Internuclear ophthalmoplegia ... Multiple Sclerosis Treatment ... management #neurology #treatment