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management algorithm causes coagulation pt abnormal aptt deficiency disorders prolonged table thrombocytopenia workup activation adultonset arterial biopsy bleeding bruising cardiology
Managing warfarin INR Warfarin dosage must be individualized according to the patient's response to the drug, and
Managing warfarin ... INR Warfarin ... management #algorithm #pharmacology ... #treatment #medications ... decisionaid #cardiology #hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Anticoagulant Medications ... , warfarin, DOACs ... ) • Advanced Liver ... table #comparison #diagnosis ... #hematology #deficiency
Initial triage of the neutropenic adult - Algorithm for the evaluation and treatment of adult patients
evaluation and treatment ... Algorithm #workup #diagnosis ... #hematology #biopsy ... #indications #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... • Reaction to Medications ... #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
or antagonism (warfarin ... inhibitor • Liver ... elevated in: • Heparin ... Thromboplastin #laboratory #hematology ... #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Anticoagulants (Warfarin ... deficiency • Liver ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Supratherapeutic warfarin ... • Reduced liver ... #differential # ... hematology #coagulation
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... fraction < 20% Differential ... splenomegaly • Hepatic ... #management #treatment ... #rheumatology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early warfarin therapy ... Early liver disease ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... family history - Medications ... : INR/PT, aPTT(liver ... #Workup #hematology
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