32 results
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... (Acute Febrile ... Fever, temperature ... #Acute #Febrile ... #Diagnosis #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Prednisone 5mg/kg ... : • Common: fever ... febrile neutrophilic ... #APML #diagnosis ... #management #hematology
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... pneumonia • Acute ... infections • Acute ... Brucellosis Faget's Sign ... #Differential #Diagnosis
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
Behcet's Syndrome ... - Diagnosis Diagnostic ... Abnormal pathergy test ... #disease #Diagnosis ... #criteria #rheumatology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
staphylococcal scalded skin syndrome ... includes Kawasaki disease ... and toxic shock syndrome ... #Diagnosis #Dermatology ... Algorithm #Nikolsky #Febrile
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Hepatorenal Syndrome ... (HRS) - Diagnostic ... Criteria HRS-AKI ... (Acute: previously ... #HRSNAKI #hepatology
STEMI Equivalents on ECG
 • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
point • De Winter syndrome ... sign A - Biphasic ... sign B - Deeply ... deviation) • Acute ... #EKG #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Periodic fever ... Liver function tests ... Histopathologic criteria ... #Diagnosis #Management ... #Hematology #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... extramedullary disease ... smear: Blasts APML ... #Leukemia #Hematology ... #Oncology #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... - ACS, AKI, acute ... WBC >100k, + lab signs ... unless worrisome EKG ... #TLS #diagnosis