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differential signs hematology management causes disease erythematosus lupus neurology sle workup acute algorithm arthritis autoimmune classification headache leukemia manifestations myositis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
Lactic acidosis Systemic ... : Systemic inflammatory ... suppression, Anemia ... liver #failure #Signs ... #Symptoms #Diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... Liver Function Tests ... #Differential #Diagnosis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... anti-synthetase syndrome ... /full triad at diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
signs/sx of inflammation ... complaints- anemia ... the “Chewing gum test ... them, but urgent rheumatology ... #Symptoms #Diagnosis
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
- Differential Diagnosis ... papilledema • Horner syndrome ... pupil (AACG) • Systemic ... symptoms and signs ... #Differential #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... • Neutropenia, anemia ... #workup #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... #signs #symptoms ... #rheumatology #
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... autoimmune disorders (Systemic ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
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