30 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Demyelinating syndromes ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... Liver Function Tests ... Liver Function Tests
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... meningitis), MCC CNS symptoms ... is a skin prick test ... #signs #symptoms ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Workup History ... (GI symptoms/endemic ... , ANA (e.g., SLE ... changes), high MCV anemia ... #hematology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... autoimmune disorders (Systemic ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... anemia • Cold ... Test: Donath-Landsteiner ... test #cold # ... #hematology #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(eg, systemic juvenile ... with leukopenia, anemia ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Carcinoma (RCC) - Diagnosis ... Anemia (common) ... Budd Chiari syndrome ... Symptoms of metastatic ... Carcinoma #RCC #Diagnosis