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diagnosis differential algorithm lymphadenopathy diffuse focal localized allergy anemia classification essential et leukemia management mcv mds myelodysplasia myelodysplastic platelets polycythemia
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Polycythemia Vera • Chronic ... : • Acute or Chronic ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... hemorrhage) • Chronic ... Myelofibrosis (MF) • Chronic ... Differential #Diagnosis #Causes ... #hematology #secondary
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... Myelofibrosis • Chronic ... BrighamChiefs #Thrombocytosis ... Differential #Diagnosis #causes ... #Platelets #hematology
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... Lymphadenopathy #LAD ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Age > 50 • Chronic ... Lymphadenopathy #LAD ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Thalassemia • Lead ... • Anemia of Chronic ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Lymphadenopathy #LAD ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... basophilia, and thrombocytosis ... #Leukemia #Hematology ... #Oncology #Diagnosis
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
2nd pass = Chronic ... • CKD/ESRD & CAD ... infections • Chronic ... Mastocytosis • Other hematologic ... Differential #Diagnosis #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... Better call hematology ... normal/high - Chronic ... hypoxia & bad oxygen ... Algorithm #workup #hematology
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