22 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
to 15 g QD • Side ... calcium for K; also binds ... nonspecifically binds ... #medications #pharmacology ... table #comparison #binders
Causes of Hypokalemia - Differential Diagnosis Algorithm
Once pseudohypokalemia is ruled out, causes of hypokalemia can be
Causes of Hypokalemia ... - Differential ... filling of bucket (low ... with the drain wide ... #Differential #
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Differential ... #Differential # ... causes #potassium #low ... #pathophysiology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... Inexpensive - Treats hypocalcemia ... effective over wide ... effective over wide ... Table #Comparison #Pharmacology
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
MECHANISM: Potassium Binder ... Most common side ... Patiromer #Potassium #Binder ... #KBinder #Hyperkalemia ... #Pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... MunerMohamed1 #hyperkalemia ... #differential # ... diagnosis #pathophysiology ... #pharmacology #
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... - Hyperkalemia ( ... Because digoxin binds ... (or low potassium
Distal Renal Tubular Acidosis
Distal RTA is the true Nephrogenic RTA and can be truly divided into
variants- the hypokalemic ... intercalated cells - A Low ... - Familial Hypokalemic ... Trimethoprim • Low ... RTA #diagnosis #differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... B-Cell ~90% • Low ... , Most common, Wide ... Classification #pathophysiology ... Diagnosis #NonHodgkin #differential
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
common in young and low ... Osteoporosis -> Low ... onto the lateral side ... orthopedics #diagnosis #differential ... #causes #pathophysiology