34 results
NSAID Selectivity Spectrum
COX-2 Selective NSAID - Celecoxib
 • Increased risk for CV events
 • Decreased risk
Increased risk for CV events ... Decreased risk for Gl side ... Decreased risk for CV events ... Cardioprotective at low ... selectivity #spectrum #pharmacology
Neuromodulators for Disorders of Gut Brain Interactions (DGBIs)
SSRIs - When anxiety, depression, and phobic features are
TCAs - First-line treatment ... sleep SNRls - Treatment ... DGBls or when side ... • Delta Ligand Agents ... Neuromodulators #DGBIs #IBS #pharmacology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... B-Cell ~90% • Low ... Responsive to Treatment ... , Most common, Wide ... Classification #pathophysiology
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
Neurological Side ... Antiparkinsonian agents ... months or years of treatment ... months or years of treatment ... #SideEffects #pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... effective oral agent ... hypoglycemia • Low ... — mitigated by slow ... #Metformin #Pharmacology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... Avoid vasodilating agents ... lidocaine, +/- pre-treatment ... Physiology: CO2: • Low ... Pressure #ICP #Pathophysiology
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia Treatment ... Algorithm ECG ... prolonged PR, wide ... removal of offending agent ... #Algorithm #Management
Treatment of Stable Wide-Complex Tachycardia
Regular
 • If ventricular tachycardia or uncertain rhythm:
    -
Treatment of Stable ... Wide-Complex Tachycardia ... Avoid AV nodal agents ... #Tachycardia #Treatment ... management #cardiology #algorithm
Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs)

What are the side effects?
 -
inhibitors and Side ... Immune-related adverse events ... What are the side ... to months after treatment ... occur at any time How
Emergency Treatment Algorithm for Convulsive Status Epilepticus
1. ABCDEFG (ABC's and Don't Ever Forget the Glucose)
2. Airway:
Emergency Treatment ... Algorithm for Convulsive ... First-line agents ... Second-line agents ... #Neurology #Pharmacology