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diagnosis hematology management dermatology lupus sle pancytopenia systemic antibodies antinuclear causes febrile neurology patterns rash syndromes vasculitis workup acquired activation
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic Diseases ... SLE), Sjogren's Syndrome ... #patterns #rheumatology ... #diagnosis #differential
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
less common diseases ... treatment can prevent ... Systemic lupus erythematosus ... polychondritis • Behcet disease ... #inflammatory #differential
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... block • Sjogren syndrome ... Treatment: • ... Summary #diagnosis #rheumatology
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
- THE ALGORITHMIC ... includes Kawasaki disease ... toxic shock syndrome ... #Rash #Algorithm ... Febrile #Fever #Differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Systemic lupus erythematosus ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #patterns #rheumatology ... #diagnosis #differential
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... Wiskott-Aldrich syndrome ... Inflammatory and ... Systemic lupus erythematosus ... #Diagnosis #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... Shrinking lung syndrome ... Serositis Labs: • ANA ... #Diagnosis #Rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... arteritis, Cogan's Syndrome ... Systemic lupus erythematosus ... swinndong #Aortitis #Differential ... #Diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... Cerebrovascular Disease ... Puncture, EEG Treatment ... CNS #neurology #rheumatology
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