13 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis ... #management #treatment
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Discontinuation of causal ... life-threatening • Treatment ... comparison #table #rheumatology ... #diagnosis #management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... Acute bacterial and ... #Algorithm #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Erythema nodosum - Acral ... - Lupus - Leukemia ... cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Workup: - ANA ... constitutional symptoms • Treatment ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Gout - Diagnosis ... sex • Metabolic syndrome ... knees, fingers, wrist ... • Acute gout treatment ... #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
culture used to diagnose ... Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... Deposition #Disease #Rheumatology ... #diagnosis #management