16 results
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Syndrome (APS) ... ): • Lupus anticoagulant ... to be present Treatment ... #Syndrome #APS ... #diagnosis #management
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS
Venous Thrombosis - Arterial Thrombosis
INR Target
Duration
Recurrence

Dr. Laurent ARNAUD
Syndrome) APS ... #Syndrome #APS ... #management #EULAR2019 ... #guidelines #rheumatology ... #hematology #treatment
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS
Previous Thrombosis?
Previous Pregnancy Complications?

Dr. Laurent ARNAUD @Lupusreference

#obstetrics
in (Antiphospholipid ... Syndrome) APS ... #Syndrome #APS ... #guidelines #rheumatology ... #obgyn #treatment
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... , others (RNP, aPL ... antibodies) • Antiphospholipid ... Antibody Syndrome
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... (for secondary APS ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Pregnancy Management in Patients with SLE and/or APS - Conception to Delivery
 • Stop Teratogenic Drugs
Pregnancy Management ... echocardiography • aPL ... #SLE #APS #lupus ... #antiphospholipid ... #syndrome #obstetrics
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #Systemic #Lupus ... Summary #diagnosis #rheumatology ... #management
Holistic Management of Systemic Lupus
 • Lifestyle interventions: Smoking cessation, Photoprotection, Therapeutic adherence, Anxiety/depression/fatigue, Fibromyagia/pain management,
Holistic Management ... of Systemic Lupus ... vaccination, Thrombosis (antiphospholipid ... SLE #Systemic #Lupus ... #treatment #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... unless severe APLS ... APML #diagnosis #management