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hematology management algorithm myelodysplastic anemia aplastic cancer chronic cll differential differentiation emergencies hemeonc leukemia lymphocytic lysis myelodysplasia oncologic platelets syndromes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... (MD) - Diagnosis ... #MDS #Diagnosis ... #Management #treatment ... #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Triggers: ATRA treatment ... #APML #diagnosis ... #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... Matthew Ho, MD
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... of the above Treatment ... Matthew Ho, MD ... #diagnosis #management ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... formed or don’t work ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... microglobulin Treatment ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
(MDS) (normal or ... Hypocellular/Hypoplastic MDS ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... full infectious work-up ... days → add fungal work-up ... (~20 %) and APL ... #HemeOnc #Diagnosis
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... Myelodysplastic syndromes ... median age at diagnosis ... #algorithm #hematology
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