15 results
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential Diagnosis ... Urticarial/LCV) - Cryoglobulinemic ... polyangiitis - EGPA ... - GPA Cutaneous ... #dermatology #rheumatology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
the context of cutaneous ... (5%): PAN > GPA ... , EGPA • Solid ... hemopathies (4%) • Cryoglobulinemia ... signs #lesions #diagnosis
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
vasculitis - Diagnosis ... , causes and management ... - French Vasculitis ... #Vasculitis #Rheumatology ... #Diagnosis #Management
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Lupus Nephritis, Cryoglobulinemia ... >>> MPA > eGPA ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
vasculitis Associated ... min/1.73 m2 at diagnosis ... • Dialysis at diagnosis ... #Vasculitis #Management ... #Rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... - GPA, EGPA, microscopic ... Henoch-Schönlein purpura) • Cutaneous ... Cryoglobulins #diagnosis ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
capillaritis • EGPA ... aphthous ulcers, cutaneous ... strong sign of cutaneous ... , EGPA, microscopic ... #rheumatology #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... /HSP • Cryoglobulinemia ... - GPA - EGPA ... #Differential #Diagnosis ... #hematology #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Differential Diagnosis ... polyangiitis • EGPA ... purpura • Mixed cryoglobulinemia ... dermatology #rash #diagnosis ... #rheumatology
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
- Differential Diagnosis ... Kaposi's sarcoma • Rheumatologic ... Autoimmune: ANCA-Assoc vasculitis ... (GPA > EGPA, MPA ... ), Cryoglobulinemia